17 Best Anime Isekai Harem with protagonist OP

The popularity of isekai harem anime with an OP protagonist has been growing quite a bit in recent years. In general, the isekai genre is one of the most famous for some years. Harem anime is another popular genre, and it is not surprising that the combination of both together with an OP protagonist delights fans. That’s why today we want to show you the best isekai harem anime with the protagonist OP.

In general, the story of an isekai begins with the death of the protagonist, who is reincarnated in a fantasy world or simply transported to another world, where a plot begins, sometimes somewhat complex. In contrast, isekai harem series with a super-powerful protagonist are usually very easy to understand, with a simple and predictable plot. They are even usually relaxing and light-hearted, with a bit of action where the MC shows the great power of his OP of him and defeats all his assailants without any effort.

So if you don’t know what to watch, this list of the best isekai harem anime with an OP protagonist will come in handy!

Note: Before you mention it to me in the comments, I haven’t included Gate, Sao, and Overlord because I don’t really consider them to be harems. With that said, here we go!

17. The Fruit of Evolution

best isekai harem anime

One fine day, a whole school full of students is teleported to a mysterious fantasy world with a role-playing game system.

One of them is Seiichi Hiragi, a student who gets bullied for being fat and ugly. While everyone else was transported in groups, he was the only one alone, which caused him to end up in a different place than the rest. When, due to fate as “the fruit of evolution”, he radically changed his life.

This anime series is a good choice if you are looking for an anime in the Arifutera style. Our protagonist becomes OP after eating the so-called evolution fruit, and his waifu transforms into a really beautiful woman. And as is known, when you become OP in an anime, you also need to start a harem.

16. High School Prodigies Have It Easy Even In Another World

best anime isekai harem with protagonist op

At first, this series seems like just another vanilla anime, but you quickly realize that it’s quite a rewarding isekai haren.

Almost from the beginning, one of the romantic leads chews her food and spits it into the lead’s mouth, as if she were a sexy mama bird. It is true that the harem lacks variety, but there is a lot of fan service and the main character is very powerful, which makes for fantastic fight scenes.

15. My Next Life As a Villainess

anime isekai harem with powerful protagonist

Idiot protagonists are my weakness, I confess. And this isekai haren anime decides to play with that kind of main character. Our protagonist, Catarina Claes, is so stupid that she helps the harem to progress. If she were a little smarter, she’d just be nice to everyone and that’s it. But instead, she sets about building a harem in her own world, which she, of course, doesn’t even realize.

It is an anime with a wide variety of character designs, with very attractive boys and girls, with very striking personalities. It’s a perfect anime series for otakus who like Ouran Host Club, but wish it was an isekai too.

14. The Greatest Demon Lord Is Reborn as a Typical Nobody

best anime isekai harem with protagonist op

The Greatest Demon Lord Is Reborn as a Typical Nobody is one of the newer OP male isekai haren anime on the list, it premiered in April 2022, and it fits perfectly on this list.

The protagonist is the most powerful being of all time, the Lord of the Demons Varvatos. But he decides to reincarnate with a lesser magical force because he is bored of leading a life with so much power. And although his reincarnation as a commoner has been quite successful, he soon realizes that he is still too powerful even so!

Obviously, the anime lets us see the typical handsome protagonist OP, who ends up staying with all the beauties he finds in his path.

13. Tenchi Muyo! War on Geminar

anime isekai haren tenchi muyo

Tenchi Muyo! War on Geminar is one of the oldest isekai anime. Many people don’t even know about this series, but it’s very good and worth watching.

The story begins with our protagonist being transported to another world, but instead of having any goal within that world, he just wants to go back home. Unfortunately, he becomes the servant of a rich and capricious princess, in addition to having to attend mecha school. And as if that were not enough, all the women he knows try to seduce him.

His physical abilities in that world are very OP, despite just going through normal training and a special diet. He had to be on the list of the best isekai haren anime.

12. The Strongest Sage With The Weakest Crest

isekai haren anime series with mc op

In this anime we have another protagonist with extraordinarily OP abilities, where others challenge him only to be ridiculed for his overwhelming powers.

Our protagonist is the strongest sage in the world, and he will stop at nothing and no one to become stronger, not even his reincarnation!

And it is that when he reincarnates in a being from the future, everyone is still incredibly pathetic compared to him. Strangely, at first everyone makes fun of him because of his weak crest, but he remains the strongest thanks to his knowledge, experience, and skills. In addition, in his journey he manages to surround himself with beautiful companions, who he ends up making powerful as well.

11. Tsukimichi -Moonlit Fantasy-

anime series Tsukimichi

Imagine an anime that takes the best fundamentals from Konosuba, Overlord, Slime, The Shield Hero and Re:Zero. And he combines them! As a result we have Tsukimichi.

The story of this anime begins with a young man being forcibly taken to another world. But instead of becoming a hero from the start, the goddess steals the hero role from him and leaves him on the brink!

Faced with such facts, our protagonist tries to create a city of monsters in which all kinds of beings can live in harmony and happiness, since he cannot speak with humans as a curse of the goddess. Instead, he understands and speaks all of the monster languages. And even if he doesn’t seem OP at first, he is, but we don’t know yet.

10. The 8th are? Are you kidding me?

The 8th Son is a hectic and fast anime, in the first three episodes we will already see the superiority of our protagonist, surpassing his teacher, he manages to become popular and manages to have a fortune.

The series revolves around a young man who wakes up in a magical fantasy world, being Wendelin von Benno Baumeister, the eighth son of the Baumeister noble family.

Since it is unlikely that he will access his father’s inheritance, he strives to improve his economic and social situation. And he discovers magic, at that moment his main objective begins to take hold. This isekai anime is an extreme case of a harem, as he has 20 wives, mistresses, and fiancées!

9.Realist Hero Rebuild the Kingdom

isekai harem series with protagonist op

Realist Hero is a relatively new anime, since it was released in 2021. The story sure sounds familiar to you, a young man is transported to a fantasy world and is given the task of helping the kingdom with his powers. Furthermore, he is fawned over by all the beautiful young women in the kingdom, from demi-human lolis to princesses.

But wait, there is something different in this isekai haren anime series, our hero bases his OP on intellect. Hence the great charm of this anime.

 This isekai anime is an extreme case of a harem, as it has 20 wives, mistresses, and fiancées!

8. Death March to the Parallel World Rhapsody

Death March to the Parallel World Rhapsody

Our protagonist, Ichirou Suzuki, is a thirtysomething programmer who one day wakes up in a fantasy world. Right away, he realizes that this world is a combination of the MMORPG games he was developing in real life. Except for his name changing, he becomes Satou, and he takes on a younger appearance, his 15 year old me.

Without having time to take it all in, he is attacked by an army of lizards, and by instinct his ability. To his surprise, he completely obliterates them and his level increases to 310, boosting his stats to almost maximum. Now with no way to return to reality and with overpowered stats, Satou embarks on a journey to explore this magical new world.

It is a funny anime with a protagonist who travels and explores the lands of an unknown world with his group of young and beautiful girls.

7. The World’s Finest Assassin

The World’s Finest Assassin is a well-detailed isekai harem anime, which embraces the popular isekai classics, without losing freshness and appeal.

In this series, we see how an old man known as the best assassin in the world dies, and is reincarnated in a world of swords and magic where his skills are necessary to prevent the destruction of the world.

Although the plot suggests that it is another isekai, what makes it special is that he was old, so in addition to his OP powers, he has a lot of combat experience and knowledge. What we also like about the series is that it doesn’t turn the protagonist into a typical pervert, but instead he is a mature, calm and educated boy.

6. In Another World with my Smartphone

In Another World with my Smartphone

In this anime, a 15-year-old student is accidentally killed by a god, and reincarnated in a fantasy world with his smartphone.

As compensation, the God gives him empowered powers, being able to use 7 types of elemental magic, Divine powers and have more strength, memory and agility. So we have a very OP protagonist, who can destroy all threats that come his way with ease.

If you are a lover of isekai haren anime with an OP protagonist, you have to watch it. By the way, our protagonist has nothing more and nothing less than 9 wives.

5. The Misfit of The Demon King Academy

The Misfit of The Demon King Academy

The Misfit of The Demon King Academy is one of the most topical isekai harem anime, with a protagonist who is so OP that he is stupid. Our protagonist is reincarnated centuries later, with overwhelming powers. He is so powerful that he beats everyone without any effort.

Also, not being a pureblood devil, he doesn’t take it seriously, since all he has is great ability. This causes his rivals to look down on him, until he overwhelms them in combat. And of course, being so successful, women notice him, having the best waifus in the series.

4. How not to Summon a Demon Lord

anime haren isekai with demon

Diablo, the protagonist of the anime, is summoned by two girls to a fantasy world where the demon king of Cross Reverie, a character from the game he has been playing lately, resides.

The beautiful girls who summoned him try to perform an enslavement ritual on him, but they make a mistake and the two end up being his slaves. And our three travel companions, after getting to know each other better, decide to travel to try to break the slave contract.

In this isekai harem anime there are quite a few ecchi scenes, beautiful waifus and a quite different protagonist than usual. And yes, Diablo is OP, but he bases his power on his equipment, with potions, a lot of experience and strategy when fighting against his rivals.

3. Arifureta

Everyone likes to see someone vulnerable and fragile rise to the top. And it is that there is some magic in the story when the protagonist starts out being the weakest and becomes the most OP character in the anime.

That is precisely what happens in Arifureta, although a little more hasty. The protagonist hates his classmates, who betray him for being the weakest. But he becomes OP after eating monster meat, evolving not only physically, but also in terms of his personality.

Although the animation and plot can be very basic, the series gains vitality with its fanservice and the brilliant transformation of the protagonist, who goes from being a piece of junk to a total badass.
2. No Game No Life

Who does not know the anime No Game No Life? It is one of the best isekai anime series based on video games, we even dare to say that it is the most famous isekai haren anime, also not only with one OP protagonist, two!

As for the plot, it is very different from the generic isekai concept, this anime is based on a couple of gamer brothers who, thanks to their great intelligence, manage to defeat their rivals. And it is that the world to which they are transported, works as if it were a video game, or you win or lose the game.

Sora, the male protagonist of NGNL has a harem full of human and demi-human waifus. Among them we can find a loli, a tsundere or a crazy one.
1. Mushoku Tensei: Jobless Reincarnation
mushoku tensei

Perhaps the story of Mushoku Tensei is the one that catches the viewer the most, that is why we have chosen it in the first place. The plot revolves around a thirty-something Neet who is killed in a car accident, but is reincarnated in a fantasy world with his memories and consciousness intact.

So far the plot is typical of any isekai anime, but the series does a great job showing us the personal development, character, and physical evolution of the male protagonist. Since he takes the second chance he has been given at life very seriously, with an incredible aptitude for magic. Furthermore, he has three wives, with whom Rudeus lives a happy life.

Each new season brings with it dozens of new isekai harem anime, in fact a time has come when you already doubt if there are any isekai without harems. And so, most isekai anime tend to have one or two waifus, but only a few have a decent story and the cast of characters necessary for a harem. In this list we have tried to find just that, a balance, not only in terms of harem, but also in action, plot, romance, etc.

I hope you liked our list of the best isekai harem anime, and if we are missing any or you would put another in the first place. Let us know in the comments section.

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